Persisting fetal clonotypes influence the structure and overlap of adult human T cell receptor repertoires

The diversity of T-cell receptors recognizing foreign pathogens is generated through a highly stochastic recombination process, making the independent production of the same sequence rare. Yet unrelated individuals do share receptors, which together constitute a “public” repertoire of abundant clono...

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Detalles Bibliográficos
Autores principales: Pogorelyy, Mikhail V., Elhanati, Yuval, Marcou, Quentin, Sycheva, Anastasiia L., Komech, Ekaterina A., Nazarov, Vadim I., Britanova, Olga V., Chudakov, Dmitriy M., Mamedov, Ilgar Z., Lebedev, Yury B., Mora, Thierry, Walczak, Aleksandra M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500008/
https://www.ncbi.nlm.nih.gov/pubmed/28683116
http://dx.doi.org/10.1371/journal.pcbi.1005572

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