The SOS and RpoS Regulons Contribute to Bacterial Cell Robustness to Genotoxic Stress by Synergistically Regulating DNA Polymerase Pol II

Mitomycin C (MMC) is a genotoxic agent that induces DNA cross-links, DNA alkylation, and the production of reactive oxygen species (ROS). MMC induces the SOS response and RpoS regulons in Escherichia coli. SOS-encoded functions are required for DNA repair, whereas the RpoS regulon is typically induc...

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Detalles Bibliográficos
Autores principales: Dapa, Tanja, Fleurier, Sébastien, Bredeche, Marie-Florence, Matic, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500135/
https://www.ncbi.nlm.nih.gov/pubmed/28468910
http://dx.doi.org/10.1534/genetics.116.199471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500135/
https://www.ncbi.nlm.nih.gov/pubmed/28468910
http://dx.doi.org/10.1534/genetics.116.199471

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