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Recombinant myostatin reduces highly expressed microRNAs in differentiating C2C12 cells

Myostatin is small glycopeptide that is produced and secreted by skeletal muscle. It is a potent negative regulator of muscle growth that has been associated with conditions of frailty. In C2C12 cells, myostatin limits cell differentiation. Myostatin acts through activin receptor IIB, activin recept...

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Detalles Bibliográficos
Autores principales: Graham, Zachary A., De Gasperi, Rita, Bauman, William A., Cardozo, Christopher P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500170/
https://www.ncbi.nlm.nih.gov/pubmed/28691106
http://dx.doi.org/10.1016/j.bbrep.2017.01.003