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In vitro and in vivo safety evaluation of Nephure™

Nephure™ is a proprietary oxalate decarboxylase (OxDC) enzyme being developed as a food ingredient. In this study, the safety of Nephure™ was evaluated in a bacterial mutagenicity assay and in a sub-chronic (13-week) oral toxicity study in rats. Nephure™ did not show any mutagenic properties in the...

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Detalles Bibliográficos
Autores principales: Cowley, Helena, Yan, Qin, Koetzner, Lee, Dolan, Laurie, Nordwald, Erik, Cowley, Aaron B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500298/
https://www.ncbi.nlm.nih.gov/pubmed/28322893
http://dx.doi.org/10.1016/j.yrtph.2017.03.016