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Epigenetic Silencing of MORT Is an Early Event in Cancer and Is Associated with Luminal, Receptor Positive Breast Tumor Subtypes

Immortality is an essential characteristic of cancer cells; a recent transcriptomic study of epithelial cell immortalization has linked epigenetic silencing of the long noncoding RNA Mortal Obligate RNA Transcript (MORT; alias ZNF667-AS1) to this process. This study evaluated the epigenetic and tran...

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Detalles Bibliográficos
Autores principales: Vrba, Lukas, Futscher, Bernard Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Breast Cancer Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500404/
https://www.ncbi.nlm.nih.gov/pubmed/28690657
http://dx.doi.org/10.4048/jbc.2017.20.2.198