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LINE-1 hypomethylation is not a common event in preneoplastic stages of gastric carcinogenesis

LINE-1 hypomethylation is widely accepted as marker for global genomic DNA hypomethylation, which is a frequent event in cancer. The aim of the study was to evaluate LINE-1 methylation status at different stages of gastric carcinogenesis and evaluate its prognostic potential in clinical settings. LI...

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Detalles Bibliográficos
Autores principales: Kupcinskas, Juozas, Steponaitiene, Ruta, Langner, Cosima, Smailyte, Giedre, Skieceviciene, Jurgita, Kupcinskas, Limas, Malfertheiner, Peter, Link, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500474/
https://www.ncbi.nlm.nih.gov/pubmed/28684753
http://dx.doi.org/10.1038/s41598-017-05143-0