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Cervical cancer stem cells manifest radioresistance: Association with upregulated AP-1 activity

Transcription factor AP-1 plays a central role in HPV-mediated cervical carcinogenesis. AP-1 has also been implicated in chemo-radio-resistance but the mechanism(s) remained unexplored. In the present study, cervical cancer stem-like cells (CaCxSLCs) isolated and enriched from cervical cancer cell l...

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Detalles Bibliográficos
Autores principales: Tyagi, Abhishek, Vishnoi, Kanchan, Kaur, Harsimrut, Srivastava, Yogesh, Roy, Bal Gangadhar, Das, Bhudev C., Bharti, Alok C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500478/
https://www.ncbi.nlm.nih.gov/pubmed/28684765
http://dx.doi.org/10.1038/s41598-017-05162-x