Mechanistic clues to the protective effect of chrysin against doxorubicin-induced cardiomyopathy: Plausible roles of p53, MAPK and AKT pathways

Doxorubicin (DOX) is the mainstay chemotherapeutic agent against a variety of human neoplasmas. However, its clinical utility is limited by its marked cardiotoxicity. Chrysin, is a natural flavone which possesses antioxidant, anti-inflammatory and anti-cancer properties. The current study aimed to i...

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Detalles Bibliográficos
Autores principales: Mantawy, Eman M., Esmat, Ahmed, El-Bakly, Wesam M., Salah ElDin, Rania A., El-Demerdash, Ebtehal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500480/
https://www.ncbi.nlm.nih.gov/pubmed/28684738
http://dx.doi.org/10.1038/s41598-017-05005-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500480/
https://www.ncbi.nlm.nih.gov/pubmed/28684738
http://dx.doi.org/10.1038/s41598-017-05005-9

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