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Development of squaraine based G-quadruplex ligands using click chemistry

The G-quadruplex (G4) structures of nucleic acids are considered to play an intrinsic role in gene expression. To this end, the development of new G4 ligands has attracted extensive research interests towards potential applications as G4-targeted drugs and molecular probes. To date, the majority of...

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Detalles Bibliográficos
Autores principales: Zhang, Xin, Wei, Yongbiao, Bing, Tao, Liu, Xiangjun, Zhang, Nan, Wang, Junyan, He, Junqing, Jin, Bing, Shangguan, Dihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500484/
https://www.ncbi.nlm.nih.gov/pubmed/28684846
http://dx.doi.org/10.1038/s41598-017-04344-x