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GdmRIII, a TetR Family Transcriptional Regulator, Controls Geldanamycin and Elaiophylin Biosynthesis in Streptomyces autolyticus CGMCC0516

Geldanamycin and elaiophylin are co-produced in several Streptomyces strains. However, the regulation of their biosynthesis is not fully understood yet. Herein the function of a TetR family regulator GdmRIII, which is located in the biosynthetic gene cluster of geldanamycin, was studied to understan...

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Detalles Bibliográficos
Autores principales: Jiang, MingXing, Yin, Min, Wu, ShaoHua, Han, XiuLin, Ji, KaiYan, Wen, MengLiang, Lu, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500506/
https://www.ncbi.nlm.nih.gov/pubmed/28684749
http://dx.doi.org/10.1038/s41598-017-05073-x