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Antiglioma effects of cytarabine on leptomeningeal metastasis of high-grade glioma by targeting the PI3K/Akt/mTOR pathway

Leptomeningeal metastasis (LM) of high-grade glioma is a highly lethal disease requiring new effective therapeutic measures. For both de novo or relapsed glioma with LM, intrathecal cytarabine chemotherapy is not frequently used for first-line and relapse protocols. We encountered a clinical case de...

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Detalles Bibliográficos
Autores principales: Zhao, Kai-Hong, Zhang, Can, Bai, Yue, Li, Yan, Kang, Xun, Chen, Jian-Xin, Yao, Kun, Jiang, Tao, Zhong, Xiao-Song, Li, Wen-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500519/
https://www.ncbi.nlm.nih.gov/pubmed/28721010
http://dx.doi.org/10.2147/DDDT.S135711