Mechanistic action of weak acid drugs on biofilms

Selective permeability of a biofilm matrix to some drugs has resulted in the development of drug tolerant bacteria. Here we studied the efficacy of a weak organic acid drug, N-acetyl-L-cysteine (NAC), on the eradication of biofilms formed by the mucoid strain of Pseudomonas aeruginosa and investigat...

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Detalles Bibliográficos
Autores principales: Kundukad, Binu, Schussman, Megan, Yang, Kaiyuan, Seviour, Thomas, Yang, Liang, Rice, Scott A., Kjelleberg, Staffan, Doyle, Patrick S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500524/
https://www.ncbi.nlm.nih.gov/pubmed/28684849
http://dx.doi.org/10.1038/s41598-017-05178-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500524/
https://www.ncbi.nlm.nih.gov/pubmed/28684849
http://dx.doi.org/10.1038/s41598-017-05178-3

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