Cell and small animal models for phenotypic drug discovery

The phenotype-based drug discovery (PDD) approach is re-emerging as an alternative platform for drug discovery. This review provides an overview of the various model systems and technical advances in imaging and image analyses that strengthen the PDD platform. In PDD screens, compounds of therapeuti...

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Detalles Bibliográficos
Autores principales: Szabo, Mihaly, Svensson Akusjärvi, Sara, Saxena, Ankur, Liu, Jianping, Chandrasekar, Gayathri, Kitambi, Satish S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500539/
https://www.ncbi.nlm.nih.gov/pubmed/28721015
http://dx.doi.org/10.2147/DDDT.S129447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500539/
https://www.ncbi.nlm.nih.gov/pubmed/28721015
http://dx.doi.org/10.2147/DDDT.S129447

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