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Cell and small animal models for phenotypic drug discovery
The phenotype-based drug discovery (PDD) approach is re-emerging as an alternative platform for drug discovery. This review provides an overview of the various model systems and technical advances in imaging and image analyses that strengthen the PDD platform. In PDD screens, compounds of therapeuti...
Autores principales: | Szabo, Mihaly, Svensson Akusjärvi, Sara, Saxena, Ankur, Liu, Jianping, Chandrasekar, Gayathri, Kitambi, Satish S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500539/ https://www.ncbi.nlm.nih.gov/pubmed/28721015 http://dx.doi.org/10.2147/DDDT.S129447 |
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