DNA binding strength increases the processivity and activity of a Y-Family DNA polymerase

DNA polymerase (pol) processivity, i.e., the bases a polymerase extends before falling off the DNA, and activity are important for copying difficult DNA sequences, including simple repeats. Y-family pols would be appealing for copying difficult DNA and incorporating non-natural dNTPs, due to their l...

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Detalles Bibliográficos
Autores principales: Wu, Jing, de Paz, Alexandra, Zamft, Bradley M., Marblestone, Adam H., Boyden, Edward S., Kording, Konrad P., Tyo, Keith E. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500549/
https://www.ncbi.nlm.nih.gov/pubmed/28684739
http://dx.doi.org/10.1038/s41598-017-02578-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500549/
https://www.ncbi.nlm.nih.gov/pubmed/28684739
http://dx.doi.org/10.1038/s41598-017-02578-3

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