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Detection of EGFR mutation in plasma using multiplex allele-specific PCR (MAS-PCR) and surface enhanced Raman spectroscopy

In this study, surface enhanced Raman spectroscopy (SERS) in combination with multiplexed polymerase chain reaction (PCR) was utilized to detect mutations of exons 19 and 21 of the epidermal growth factor receptor (EGFR) gene. Through the use of multiplexed PCR, the two mutation types were amplified...

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Detalles Bibliográficos
Autores principales: Li, Xiaozhou, Yang, Tianyue, Li, Caesar Siqi, Wang, Deli, Song, Youtao, Jin, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500569/
https://www.ncbi.nlm.nih.gov/pubmed/28684733
http://dx.doi.org/10.1038/s41598-017-05050-4