Identification of Histamine H(3) Receptor Ligands Using a New Crystal Structure Fragment-based Method

Virtual screening offers an efficient alternative to high-throughput screening in the identification of pharmacological tools and lead compounds. Virtual screening is typically based on the matching of target structures or ligand pharmacophores to commercial or in-house compound catalogues. This stu...

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Detalles Bibliográficos
Autores principales: Frandsen, Ida Osborn, Boesgaard, Michael W., Fidom, Kimberley, Hauser, Alexander S., Isberg, Vignir, Bräuner-Osborne, Hans, Wellendorph, Petrine, Gloriam, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500575/
https://www.ncbi.nlm.nih.gov/pubmed/28684785
http://dx.doi.org/10.1038/s41598-017-05058-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500575/
https://www.ncbi.nlm.nih.gov/pubmed/28684785
http://dx.doi.org/10.1038/s41598-017-05058-w

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