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Identification of Histamine H(3) Receptor Ligands Using a New Crystal Structure Fragment-based Method

Virtual screening offers an efficient alternative to high-throughput screening in the identification of pharmacological tools and lead compounds. Virtual screening is typically based on the matching of target structures or ligand pharmacophores to commercial or in-house compound catalogues. This stu...

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Detalles Bibliográficos
Autores principales:	Frandsen, Ida Osborn, Boesgaard, Michael W., Fidom, Kimberley, Hauser, Alexander S., Isberg, Vignir, Bräuner-Osborne, Hans, Wellendorph, Petrine, Gloriam, David E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500575/ https://www.ncbi.nlm.nih.gov/pubmed/28684785 http://dx.doi.org/10.1038/s41598-017-05058-w

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