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ZB-16, a Novel GPR119 Agonist, Relieves the Severity of Streptozotocin–Nicotinamide-Induced Diabetes in Rats

GPR119 is involved in the regulation of incretin and insulin secretion, so the GPR119 agonists have been suggested as novel antidiabetic medications. The purpose of this work was to assess the influence of novel GPR119 agonist ZB-16 on the glucose utilization, insulin, and glucagon-like peptide-1 (G...

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Detalles Bibliográficos
Autores principales: Tyurenkov, Ivan N., Kurkin, Denis V., Bakulin, Dmitry A., Volotova, Elena V., Chafeev, Mikhail A., Smirnov, Alexey V., Morkovin, Evgeny I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500613/
https://www.ncbi.nlm.nih.gov/pubmed/28736546
http://dx.doi.org/10.3389/fendo.2017.00152