Cargando…

β-Glucan Size Controls Dectin-1-Mediated Immune Responses in Human Dendritic Cells by Regulating IL-1β Production

Dectin-1/CLEC7A is a pattern recognition receptor that recognizes β-1,3 glucans, and its stimulation initiates signaling events characterized by the production of inflammatory cytokines from human dendritic cells (DCs) required for antifungal immunity. β-glucans differ greatly in size, structure, an...

Descripción completa

Detalles Bibliográficos
Autores principales: Elder, Matthew J., Webster, Steve J., Chee, Ronnie, Williams, David L., Hill Gaston, J. S., Goodall, Jane C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500631/
https://www.ncbi.nlm.nih.gov/pubmed/28736555
http://dx.doi.org/10.3389/fimmu.2017.00791