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β-Glucan Size Controls Dectin-1-Mediated Immune Responses in Human Dendritic Cells by Regulating IL-1β Production
Dectin-1/CLEC7A is a pattern recognition receptor that recognizes β-1,3 glucans, and its stimulation initiates signaling events characterized by the production of inflammatory cytokines from human dendritic cells (DCs) required for antifungal immunity. β-glucans differ greatly in size, structure, an...
Autores principales: | Elder, Matthew J., Webster, Steve J., Chee, Ronnie, Williams, David L., Hill Gaston, J. S., Goodall, Jane C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500631/ https://www.ncbi.nlm.nih.gov/pubmed/28736555 http://dx.doi.org/10.3389/fimmu.2017.00791 |
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