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Cytoplasmic E2f4 forms organizing centres for initiation of centriole amplification during multiciliogenesis

Abnormal development of multiciliated cells is a hallmark of a variety of human conditions associated with chronic airway diseases, hydrocephalus and infertility. Multiciliogenesis requires both activation of a specialized transcriptional program and assembly of cytoplasmic structures for large-scal...

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Detalles Bibliográficos
Autores principales: Mori, Munemasa, Hazan, Renin, Danielian, Paul S., Mahoney, John E., Li, Huijun, Lu, Jining, Miller, Emily S., Zhu, Xueliang, Lees, Jacqueline A., Cardoso, Wellington V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500891/
https://www.ncbi.nlm.nih.gov/pubmed/28675157
http://dx.doi.org/10.1038/ncomms15857