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Cytoplasmic E2f4 forms organizing centres for initiation of centriole amplification during multiciliogenesis
Abnormal development of multiciliated cells is a hallmark of a variety of human conditions associated with chronic airway diseases, hydrocephalus and infertility. Multiciliogenesis requires both activation of a specialized transcriptional program and assembly of cytoplasmic structures for large-scal...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500891/ https://www.ncbi.nlm.nih.gov/pubmed/28675157 http://dx.doi.org/10.1038/ncomms15857 |