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TnseqDiff: identification of conditionally essential genes in transposon sequencing studies

BACKGROUND: Tn-Seq is a high throughput technique for analysis of transposon mutant libraries to determine conditional essentiality of a gene under an experimental condition. A special feature of the Tn-seq data is that multiple mutants in a gene provides independent evidence to prioritize that gene...

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Detalles Bibliográficos
Autores principales: Zhao, Lili, Anderson, Mark T., Wu, Weisheng, T. Mobley, Harry L., Bachman, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500955/
https://www.ncbi.nlm.nih.gov/pubmed/28683752
http://dx.doi.org/10.1186/s12859-017-1745-2