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GeneBreak: detection of recurrent DNA copy number aberration-associated chromosomal breakpoints within genes
Development of cancer is driven by somatic alterations, including numerical and structural chromosomal aberrations. Currently, several computational methods are available and are widely applied to detect numerical copy number aberrations (CNAs) of chromosomal segments in tumor genomes. However, ther...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000Research
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500957/ https://www.ncbi.nlm.nih.gov/pubmed/28713543 http://dx.doi.org/10.12688/f1000research.9259.2 |