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GeneBreak: detection of recurrent DNA copy number aberration-associated chromosomal breakpoints within genes

Development of cancer is driven by somatic alterations, including numerical and structural chromosomal aberrations. Currently, several computational methods are available and are widely applied to detect numerical copy number aberrations (CNAs) of chromosomal segments in tumor genomes. However, ther...

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Detalles Bibliográficos
Autores principales:	van den Broek, Evert, van Lieshout, Stef, Rausch, Christian, Ylstra, Bauke, van de Wiel, Mark A., Meijer, Gerrit A., Fijneman, Remond J.A., Abeln, Sanne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	F1000Research 2017
Materias:	Software Tool Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500957/ https://www.ncbi.nlm.nih.gov/pubmed/28713543 http://dx.doi.org/10.12688/f1000research.9259.2

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