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Uncovering missing pieces: duplication and deletion history of arrestins in deuterostomes

BACKGROUND: The cytosolic arrestin proteins mediate desensitization of activated G protein-coupled receptors (GPCRs) via competition with G proteins for the active phosphorylated receptors. Arrestins in active, including receptor-bound, conformation are also transducers of signaling. Therefore, this...

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Detalles Bibliográficos
Autores principales: Indrischek, Henrike, Prohaska, Sonja J., Gurevich, Vsevolod V., Gurevich, Eugenia V., Stadler, Peter F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501109/
https://www.ncbi.nlm.nih.gov/pubmed/28683816
http://dx.doi.org/10.1186/s12862-017-1001-4