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Coordinating heart morphogenesis: A novel role for hyperpolarization-activated cyclic nucleotide-gated (HCN) channels during cardiogenesis in Xenopus laevis

Hyperpolarization-activated cyclic-nucleotide gated channel (HCN) proteins are important regulators of both neuronal and cardiac excitability. Among the 4 HCN isoforms, HCN4 is known as a pacemaker channel, because it helps control the periodicity of contractions in vertebrate hearts. Although the p...

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Detalles Bibliográficos
Autores principales: Pitcairn, Emily, Harris, Hannah, Epiney, Justine, Pai, Vaibhav P., Lemire, Joan M., Ye, Bin, Shi, Nian-Qing, Levin, Michael, McLaughlin, Kelly A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501196/
https://www.ncbi.nlm.nih.gov/pubmed/28702127
http://dx.doi.org/10.1080/19420889.2017.1309488