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Mechano growth factor, a splice variant of IGF-1, promotes neurogenesis in the aging mouse brain

Mechano growth factor (MGF) is a splice variant of IGF-1 first described in skeletal muscle. MGF induces muscle cell proliferation in response to muscle stress and injury. In control mice we found endogenous expression of MGF in neurogenic areas of the brain and these levels declined with age. To be...

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Detalles Bibliográficos
Autores principales: Tang, Jason J., Podratz, Jewel L., Lange, Miranda, Scrable, Heidi J., Jang, Mi-Hyeon, Windebank, Anthony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501366/
https://www.ncbi.nlm.nih.gov/pubmed/28683812
http://dx.doi.org/10.1186/s13041-017-0304-0