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Mechano growth factor, a splice variant of IGF-1, promotes neurogenesis in the aging mouse brain
Mechano growth factor (MGF) is a splice variant of IGF-1 first described in skeletal muscle. MGF induces muscle cell proliferation in response to muscle stress and injury. In control mice we found endogenous expression of MGF in neurogenic areas of the brain and these levels declined with age. To be...
Autores principales: | Tang, Jason J., Podratz, Jewel L., Lange, Miranda, Scrable, Heidi J., Jang, Mi-Hyeon, Windebank, Anthony J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501366/ https://www.ncbi.nlm.nih.gov/pubmed/28683812 http://dx.doi.org/10.1186/s13041-017-0304-0 |
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