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Chemosensitizing indomethacin-conjugated dextran-based micelles for effective delivery of paclitaxel in resistant breast cancer therapy

Multidrug resistance (MDR) against chemotherapeutic agents has become the major obstacle to successful cancer therapy and multidrug resistance-associated proteins (MRPs) mediated drug efflux is the key factor for MDR. Indomethacin (IND), one of the non-steroidal anti-inflammatory agents, has been de...

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Detalles Bibliográficos
Autores principales: Ji, Weiping, Wang, Bo, Fan, Qiuping, Xu, Chao, He, Youwu, Chen, Youfen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501509/
https://www.ncbi.nlm.nih.gov/pubmed/28686704
http://dx.doi.org/10.1371/journal.pone.0180037