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Comparative proteomic analysis of Gib2 validating its adaptor function in Cryptococcus neoformans

Cryptococcus neoformans causes often-fatal fungal meningoencephalitis in immunocompromised individuals. While the exact disease mechanisms remain elusive, signal transduction pathways mediated by key elements such as G-protein α subunit Gpa1, small GTPase Ras1, and atypical Gβ-like/RACK1 protein Gib...

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Detalles Bibliográficos
Autores principales: Bruni, Gillian O., Battle, Blake, Kelly, Ben, Zhang, Zhengguang, Wang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501510/
https://www.ncbi.nlm.nih.gov/pubmed/28686685
http://dx.doi.org/10.1371/journal.pone.0180243