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CD4/CD8/Dendritic cell complexes in the spleen: CD8(+) T cells can directly bind CD4(+) T cells and modulate their response

CD4(+) T cell help to CD8(+) T cell responses requires that CD4(+) and CD8(+) T cells interact with the same antigen presenting dendritic cell (Ag(+)DC), but it remains controversial whether helper signals are delivered indirectly through a licensed DC and/or involve direct CD4(+)/CD8(+) T cell cont...

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Detalles Bibliográficos
Autores principales: Barinov, Aleksandr, Galgano, Alessia, Krenn, Gerald, Tanchot, Corinne, Vasseur, Florence, Rocha, Benedita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501581/
https://www.ncbi.nlm.nih.gov/pubmed/28686740
http://dx.doi.org/10.1371/journal.pone.0180644