Assessment of circulating copy number variant detection for cancer screening

Current high-sensitivity cancer screening methods, largely utilizing correlative biomarkers, suffer from false positive rates that lead to unnecessary medical procedures and debatable public health benefit overall. Detection of circulating tumor DNA (ctDNA), a causal biomarker, has the potential to...

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Detalles Bibliográficos
Autores principales: Molparia, Bhuvan, Nichani, Eshaan, Torkamani, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501586/
https://www.ncbi.nlm.nih.gov/pubmed/28686671
http://dx.doi.org/10.1371/journal.pone.0180647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501586/
https://www.ncbi.nlm.nih.gov/pubmed/28686671
http://dx.doi.org/10.1371/journal.pone.0180647

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