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Engineering of monobody conjugates for human EphA2-specific optical imaging

In a previous study, we developed an E1 monobody specific for the tumor biomarker hEphA2 [PLoS ONE (2015) 10(7): e0132976]. E1 showed potential as a molecular probe for in vitro and in vivo targeting of cancers overexpressing hEphA2. In the present study, we constructed expression vectors for E1 con...

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Detalles Bibliográficos
Autores principales: Kim, Min-A, Yoon, Hee Seung, Park, Seung-Hwan, Kim, Dong-Yeon, Pyo, Ayoung, Kim, Hyeon Sik, Min, Jung-Joon, Hong, Yeongjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501600/
https://www.ncbi.nlm.nih.gov/pubmed/28686661
http://dx.doi.org/10.1371/journal.pone.0180786