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Flow velocity-driven differentiation of human mesenchymal stromal cells in silk fibroin scaffolds: A combined experimental and computational approach

Mechanical loading plays a major role in bone remodeling and fracture healing. Mimicking the concept of mechanical loading of bone has been widely studied in bone tissue engineering by perfusion cultures. Nevertheless, there is still debate regarding the in-vitro mechanical stimulation regime. This...

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Detalles Bibliográficos
Autores principales: Vetsch, Jolanda Rita, Betts, Duncan Colin, Müller, Ralph, Hofmann, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501602/
https://www.ncbi.nlm.nih.gov/pubmed/28686698
http://dx.doi.org/10.1371/journal.pone.0180781