GSR is not essential for the maintenance of antioxidant defenses in mouse cochlea: Possible role of the thioredoxin system as a functional backup for GSR

Glutathione reductase (GSR), a key member of the glutathione antioxidant defense system, converts oxidized glutathione (GSSG) to reduced glutathione (GSH) and maintains the intracellular glutathione redox state to protect the cells from oxidative damage. Previous reports have shown that Gsr deficien...

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Detalles Bibliográficos
Autores principales: Han, Chul, Kim, Mi-Jung, Ding, Dalian, Park, Hyo-Jin, White, Karessa, Walker, Logan, Gu, Tongjun, Tanokura, Masaru, Yamasoba, Tatsuya, Linser, Paul, Salvi, Richard, Someya, Shinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501606/
https://www.ncbi.nlm.nih.gov/pubmed/28686716
http://dx.doi.org/10.1371/journal.pone.0180817

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501606/
https://www.ncbi.nlm.nih.gov/pubmed/28686716
http://dx.doi.org/10.1371/journal.pone.0180817

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