MDR1A deficiency restrains tumor growth in murine colitis-associated carcinogenesis

Patients with Ulcerative Colitis (UC) have an increased risk to develop colitis-associated colorectal cancer (CAC). Here, we found that protein expression of ABCB1 (ATP Binding Cassette Subfamily B Member 1) / MDR1 (multidrug resistance 1) was diminished in the intestinal mucosa of patients with act...

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Detalles Bibliográficos
Autores principales: Hennenberg, Eva Maria, Eyking, Annette, Reis, Henning, Cario, Elke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501609/
https://www.ncbi.nlm.nih.gov/pubmed/28686677
http://dx.doi.org/10.1371/journal.pone.0180834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501609/
https://www.ncbi.nlm.nih.gov/pubmed/28686677
http://dx.doi.org/10.1371/journal.pone.0180834

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