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Transcriptome-wide comparison of the impact of Atoh1 and miR-183 family on pluripotent stem cells and multipotent otic progenitor cells

Over 5% of the global population suffers from disabling hearing loss caused by multiple factors including aging, noise exposure, genetic predisposition, or use of ototoxic drugs. Sensorineural hearing loss is often caused by the loss of sensory hair cells (HCs) of the inner ear. A barrier to hearing...

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Detalles Bibliográficos
Autores principales: Ebeid, Michael, Sripal, Prashanth, Pecka, Jason, Beisel, Kirk W., Kwan, Kelvin, Soukup, Garrett A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501616/
https://www.ncbi.nlm.nih.gov/pubmed/28686713
http://dx.doi.org/10.1371/journal.pone.0180855