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Intracellular interactions of umeclidinium and vilanterol in human airway smooth muscle

BACKGROUND: Intracellular mechanisms of action of umeclidinium (UMEC), a long-acting muscarinic receptor antagonist, and vilanterol (VI), a long-acting β(2)-adrenoceptor (β(2)R) agonist, were investigated in target cells: human airway smooth-muscle cells (ASMCs). MATERIALS AND METHODS: ASMCs from tr...

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Detalles Bibliográficos
Autores principales: Shaikh, Nooreen, Johnson, Malcolm, Hall, David A, Chung, Kian Fan, Riley, John H, Worsley, Sally, Bhavsar, Pankaj K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501633/
https://www.ncbi.nlm.nih.gov/pubmed/28721035
http://dx.doi.org/10.2147/COPD.S134420