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Plasminogen Tochigi mice exhibit phenotypes similar to wild-type mice under experimental thrombotic conditions

Plasminogen (Plg) is a precursor of plasmin that degrades fibrin. A race-specific A620T mutation in Plg, also known as Plg-Tochigi, originally identified in a patient with recurrent venous thromboembolism, causes dysplasminogenemia with reduced plasmin activity. The Plg-A620T mutation is present in...

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Detalles Bibliográficos
Autores principales: Tashima, Yuko, Banno, Fumiaki, Kita, Toshiyuki, Matsuda, Yasuyuki, Yanamoto, Hiroji, Miyata, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501636/
https://www.ncbi.nlm.nih.gov/pubmed/28686706
http://dx.doi.org/10.1371/journal.pone.0180981