Lack of a peroxiredoxin suppresses the lethality of cells devoid of electron donors by channelling electrons to oxidized ribonucleotide reductase

The thioredoxin and glutaredoxin pathways are responsible of recycling several enzymes which undergo intramolecular disulfide bond formation as part of their catalytic cycles such as the peroxide scavengers peroxiredoxins or the enzyme ribonucleotide reductase (RNR). RNR, the rate-limiting enzyme of...

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Detalles Bibliográficos
Autores principales: Boronat, Susanna, Domènech, Alba, Carmona, Mercè, García-Santamarina, Sarela, Bañó, M. Carmen, Ayté, José, Hidalgo, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501661/
https://www.ncbi.nlm.nih.gov/pubmed/28640807
http://dx.doi.org/10.1371/journal.pgen.1006858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501661/
https://www.ncbi.nlm.nih.gov/pubmed/28640807
http://dx.doi.org/10.1371/journal.pgen.1006858

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