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Effect of praziquantel on the differential expression of mouse hepatic genes and parasite ATP binding cassette transporter gene family members during Schistosoma mansoni infection

Schistosomiasis is a chronic parasitic disease caused by sexually dimorphic blood flukes of the genus Schistosoma. Praziquantel (PZQ) is the only drug widely available to treat the disease but does not kill juvenile parasites. Here we report the use of next generation sequencing to study the transcr...

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Detalles Bibliográficos
Autores principales: Sanchez, Melissa C., Krasnec, Katina V., Parra, Amalia S., von Cabanlong, Christian, Gobert, Geoffrey N., Umylny, Boris, Cupit, Pauline M., Cunningham, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501684/
https://www.ncbi.nlm.nih.gov/pubmed/28650976
http://dx.doi.org/10.1371/journal.pntd.0005691