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Effect of praziquantel on the differential expression of mouse hepatic genes and parasite ATP binding cassette transporter gene family members during Schistosoma mansoni infection
Schistosomiasis is a chronic parasitic disease caused by sexually dimorphic blood flukes of the genus Schistosoma. Praziquantel (PZQ) is the only drug widely available to treat the disease but does not kill juvenile parasites. Here we report the use of next generation sequencing to study the transcr...
Autores principales: | Sanchez, Melissa C., Krasnec, Katina V., Parra, Amalia S., von Cabanlong, Christian, Gobert, Geoffrey N., Umylny, Boris, Cupit, Pauline M., Cunningham, Charles |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501684/ https://www.ncbi.nlm.nih.gov/pubmed/28650976 http://dx.doi.org/10.1371/journal.pntd.0005691 |
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