Comparison of two neurotrophic serpins reveals a small fragment with cell survival activity

PURPOSE: Protease nexin-1 (PN-1), a serpin encoded by the SERPINE2 gene, has serine protease inhibitory activity and neurotrophic properties in the brain. PN-1 inhibits retinal angiogenesis; however, PN-1’s neurotrophic capacities in the retina have not yet been evaluated. Pigment epithelium-derived...

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Detalles Bibliográficos
Autores principales: Winokur, Paige N., Subramanian, Preeti, Bullock, Jeanee L., Arocas, Veronique, Becerra, S. Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501690/
https://www.ncbi.nlm.nih.gov/pubmed/28706437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501690/
https://www.ncbi.nlm.nih.gov/pubmed/28706437

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