Genistein suppresses retinoblastoma cell viability and growth and induces apoptosis by upregulating miR-145 and inhibiting its target ABCE1

PURPOSE: Retinoblastoma is a rare malignancy in developing retina tissue in children with limited therapeutic options. Here we sought to investigate the potential clinical value of genistein, the phytoestrogen derived from the soybean with antioxidant activity, in this disease. METHODS: Retinoblasto...

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Detalles Bibliográficos
Autores principales: Wei, Dong, Yang, Lieying, Lv, Bo, Chen, Lijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501691/
https://www.ncbi.nlm.nih.gov/pubmed/28706438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501691/
https://www.ncbi.nlm.nih.gov/pubmed/28706438

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