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A human endogenous retrovirus-derived gene that can contribute to oncogenesis by activating the ERK pathway and inducing migration and invasion

Endogenous retroviruses are cellular genes of retroviral origin captured by their host during the course of evolution and represent around 8% of the human genome. Although most are defective and transcriptionally silenced, some are still able to generate retroviral-like particles and proteins. Among...

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Detalles Bibliográficos
Autores principales: Lemaître, Cécile, Tsang, Jhen, Bireau, Caroline, Heidmann, Thierry, Dewannieux, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501692/
https://www.ncbi.nlm.nih.gov/pubmed/28651004
http://dx.doi.org/10.1371/journal.ppat.1006451