The pre-rRNA processing factor DEF is rate limiting for the pathogenesis of MYCN-driven neuroblastoma

The nucleolar factor, digestive organ expansion factor (DEF), has a key role in ribosome biogenesis, functioning in pre-ribosomal RNA (pre-rRNA) processing as a component of the small ribosomal subunit (SSU) processome. Here we show that the peripheral sympathetic nervous system (PSNS) is very under...

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Detalles Bibliográficos
Autores principales: Tao, T, Sondalle, S B, Shi, H, Zhu, S, Perez-Atayde, A R, Peng, J, Baserga, S J, Look, A T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501763/
https://www.ncbi.nlm.nih.gov/pubmed/28263972
http://dx.doi.org/10.1038/onc.2016.527

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501763/
https://www.ncbi.nlm.nih.gov/pubmed/28263972
http://dx.doi.org/10.1038/onc.2016.527

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