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Inhibition of highly pathogenic avian influenza (HPAI) virus by a peptide derived from vFLIP through its direct destabilization of viruses

The antiviral activities of synthesized Kα2-helix peptide, which was derived from the viral FLICE-like inhibitor protein (vFLIP) of Kaposi’s sarcoma-associated herpesvirus (KSHV), against influenza A virus (IAV) were investigated in vitro and in vivo, and mechanisms of action were suggested. In addi...

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Detalles Bibliográficos
Autores principales: Moon, Ho-Jin, Nikapitiya, Chamilani, Lee, Hyun-Cheol, Park, Min-Eun, Kim, Jae-Hoon, Kim, Tae-Hwan, Yoon, Ji-Eun, Cho, Won-Kyung, Ma, Jin Yeul, Kim, Chul-Joong, Jung, Jae U., Lee, Jong-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501782/
https://www.ncbi.nlm.nih.gov/pubmed/28687749
http://dx.doi.org/10.1038/s41598-017-04777-4