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Genetic variants of TRAF6 modulate peritoneal immunity and the risk of spontaneous bacterial peritonitis in cirrhosis: A combined prospective-retrospective study

Alterations of the innate immunity contribute to the development of spontaneous bacterial peritonitis (SBP) in liver cirrhosis. Given its role in immune signaling, antimicrobial function, and macrophage differentiation, we hypothesized that genetic polymorphisms of TRAF6 modulate the risk of SBP. Th...

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Detalles Bibliográficos
Autores principales: Mai, Martina, Stengel, Sven, Al-Herwi, Eihab, Peter, Jack, Schmidt, Caroline, Rubio, Ignacio, Stallmach, Andreas, Bruns, Tony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501819/
https://www.ncbi.nlm.nih.gov/pubmed/28687809
http://dx.doi.org/10.1038/s41598-017-04895-z